Jacob E. Lemieux

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Jacob Lemieux, MD, PhD

Jacob Lemieux was a post-doctoral researcher in the Sabeti Lab and is an infectious diseases staff physician at Massachusetts General Hospital. He holds a B.S. from Stanford University, a D.Phil. in molecular parasitology from Oxford University, where he was a Rhodes Scholar and member of the NIH-Oxford Graduate Partnership Program, and an M.D. from Harvard Medical School. He is interested in the genetics and pathophysiology of red blood cell parasites, tick-borne diseases, and respiratory viruses.
“The Lemieux lab integrates computational and experimental studies of microbial genetic variation to understand how pathogens spread in the population and cause disease in human hosts. Our studies focus on Borrelia burgdorferi, the bacterial agent of Lyme disease, and SARS-CoV-2, the cause of COVID-19. Major projects in the lab include the use of computational screens and genome-wide association studies to identify microbial genes associated with disease phenotypes, for both Lyme disease and COVID-19, followed by the use of reverse genetic tools to characterize mechanisms of disease-associated loci in experimental systems.”